JP Journal of Biostatistics

The JP Journal of Biostatistics is a highly regarded open-access international journal indexed in the Emerging Sources Citation Index (ESCI). It focuses on the application of statistical theory and methods in resolving problems in biological, biomedical, and agricultural sciences. The journal encourages the submission of experimental papers that employ relevant algorithms and also welcomes survey articles in the fields of biostatistics and epidemiology.

Submit Article

ENHANCING MEDICATION ADHERENCE IN HEART FAILURE PATIENTS: AN EMPIRICAL STUDY OF PERSUASIVE TECHNOLOGY STRATEGIES

Authors

  • Osamah A. Altammami

Keywords:

heart failure, medication adherence, persuasive technology intervention, medication dispensers, pill boxes

DOI:

https://doi.org/10.17654/0973514324021

Abstract

Global healthcare systems have a great deal of difficulty in treating heart failure (HF), and proper drug adherence is essential to the long-term management of this illness. Even though a number of interventions have been suggested to improve medication adherence in heart failure patients, further research is still needed to determine whether persuasive technology tactics are effective in this situation. The study poses a comparison between treatment approaches and an array of persuasive technologies to facilitate medication adherence in the case of heart failure patients and impacts the implementation of these persuasive strategies by moderating factors. The main purpose of this study is to improve the quality of life of heart failure patients with the execution of experimental research on enhancing adherence through the persuasive arguments program by using a two-group pre-and post-test design with 50 patients who were sampled through convenience sampling. As for the study group, standard care was given to the control group in the form of pillboxes and education booklets, while persuasive technology strategies such as electronic medication dispensers were used in the experimental group. Medication adherence measurement has been executed via Medication Adherence Ratio formula and the statistical analysis were run to compare and assess various therapies. Despite the patients’ demographics, this study noteworthy reveals that persuasive technological tools have a pivotal role in increasing adherence to medications coupled with better health outcomes for heart failure patients. Researchers and public health officials must cross-dress persuasive technology into clinical practice, take action to encourage the adoption by means of costs and accessibility, and give the priority to the ones that will be more long-term to find out how the technology will be effective and scalable in healthcare places for the realization of the benefits.

Received: June 2, 2024;
Accepted: June 28, 2024

References

A. Ahmad, V. Chiu and M. A. Arain, Users’ perceptions of an in-home electronic medication dispensing system: a qualitative study, Medical devices: Evidence and Research (2020), 31-39.

S. S. Allemann, K. E. Hersberger and I. Arnet, Patient views on an electronic dispensing device for prepackaged polypharmacy: a qualitative assessment in an ambulatory setting, Integrated Pharmacy Research and Practice (2015), 167-174.

M. A. Arain, A. Ahmad, V. Chiu and L. Kembel, Medication adherence support of an in-home electronic medication dispensing system for individuals living with chronic conditions: a pilot randomized controlled trial, BMC Geriatrics 21(1) (2021), 1-16.

K. E. Bergethon, C. Ju, A. D. DeVore, N. C. Hardy, G. C. Fonarow, C. W. Yancy and A. F. Hernandez, Trends in 30-day readmission rates for patients hospitalized with heart failure: findings from the get with the guidelines-heart failure registry, Circulation: Heart Failure 9(6) (2016), e002594.

K. C. Buckwalter, B. J. Wakefield, B. Hanna and J. Lehmann, New technology for medication adherence: electronically managed medication dispensing system, Journal of Gerontological Nursing 30(7) (2004), 5-8.

S. Chatterjee and A. Price, Healthy living with persuasive technologies: framework, issues, and challenges, Journal of the American Medical Informatics Association 16(2) (2009), 171-178.

V. W. S. Cheng, T. Davenport, D. Johnson, K. Vella and I. B. Hickie, Gamification in apps and technologies for improving mental health and well-being: systematic review, JMIR Mental Health 6(6) (2019), e13717.

N. A. Cruz-Ramos, G. Alor-Hernández, L. O. Colombo-Mendoza, J. L. Sánchez-Cervantes, L. Rodríguez-Mazahua and L. R. Guarneros-Nolasco, mHealth apps for self-management of cardiovascular diseases: a scoping review, Healthcare 10(2) (2022), 322.

M. H. da Fonseca, F. Kovaleski, C. T. Picinin, B. Pedroso and P. Rubbo, E-health practices and technologies: a systematic review from 2014 to 2019, Healthcare 9(9) (2021), 1192.

M. W. Davis, M. J. Kirwan, W. N. Maclay and H. P. Pappas, (Eds.), Closing the Care Gap with Wearable Devices: Innovating Healthcare with Wearable Patient Monitoring, CRC Press, 2022.

K. Dharmarajan, A. F. Hsieh, Z. Lin, H. Bueno, J. S. Ross, L. I. Horwitz and H. M. Krumholz, Diagnoses and timing of 30-day readmissions after hospitalization for heart failure, acute myocardial infarction, or pneumonia, JAMA 309(4) (2013), 355-363.

K. Dyb, G. R. Berntsen and L. Kvam, Adopt, adapt, or abandon technology-supported person-centred care initiatives: healthcare providers’ beliefs matter, BMC Health Services Research 21 (2021), 1-13.

C. I. Fernandez-Lazaro, J. M. García-González, D. P. Adams, D. Fernandez-Lazaro, J. Mielgo-Ayuso, A. Caballero-Garcia and J. A. Miron-Canelo, Adherence to treatment and related factors among patients with chronic conditions in primary care: a cross-sectional study, BMC Family Practice 20(1) (2019), 1-12.

B. J. Fogg, Persuasive technology: using computers to change what we think and do, Ubiquity, 2002.

A. Groenewegen, F. H. Rutten, A. Mosterd and A. W. Hoes, Epidemiology of heart failure, European Journal of Heart Failure 22(8) (2020), 1342-1356.

S. C. Inglis, R. A. Clark, R. Dierckx, D. Prieto-Merino and J. G. Cleland, Structured telephone support or non-invasive telemonitoring for patients with heart failure, Heart (2016).

A. Jo, E. Ji Seo and Y. J. Son, The roles of health literacy and social support in improving adherence to self-care behaviours among older adults with heart failure, Nursing Open 7(6) (2020), 2039-2046.

H. Kip, J. Keizer, M. C. da Silva, N. Beerlage-de Jong, N. Köhle and S. M. Kelders, Methods for human-centered eHealth development: narrative scoping review, Journal of Medical Internet Research 24(1) (2022), e31858.

S. Kitsiou, B. S. Gerber, M. M. Kansal, S. W. Buchholz, J. Chen, T. Ruppar and S. J. Pressler, Patient-centered mobile health technology intervention to improve self-care in patients with chronic heart failure: protocol for a feasibility randomized controlled trial, Contemporary Clinical Trials 106 (2021), 106433.

S. Kitsiou, G. Paré, M. Jaana and B. Gerber, Effectiveness of mHealth interventions for patients with diabetes: an overview of systematic reviews, PloS One 12(3) (2017), e0173160.

H. M. Krumholz, J. Amatruda, G. L. Smith, J. A. Mattera, S. A. Roumanis, M. J. Radford and V. Vaccarino, Randomized trial of an education and support intervention to prevent readmission of patients with heart failure, Journal of the American College of Cardiology 39(1) (2002), 83-89.

G. Lau, J. Ho, S. Lin, K. Yeoh, T. Wan and M. Hodgkinson, Patient and clinician perspectives of an integrated electronic medication prescribing and dispensing system: a qualitative study at a multisite Australian hospital network, Health Information Management Journal 48(1) (2019), 12-23.

R. Maddison, Y. Jiang, R. Stewart, T. Scott, A. Kerr, R. Whittaker and L. Dale, An intervention to improve medication adherence in people with heart disease (Text4HeartII): Randomized controlled trial, JMIR mHealth and uHealth 9(6) (2021), e24952.

N. Masnoon, S. Shakib, L. Kalisch-Ellett and G. E. Caughey, What is polypharmacy? A systematic review of definitions, BMC Geriatrics 17 (2017), 1-10.

B. Miranda, C. Jere, O. Alharbi, S. Lakshmi, Y. Khouja and S. Chatterjee, Examining the efficacy of a persuasive technology package in reducing texting and driving behavior, Persuasive Technology: 8th International Conference, PERSUASIVE 2013, Sydney, NSW, Australia, April 3-5, 2013, Proceedings 8, Springer Berlin Heidelberg, 2013, pp. 137-148.

O. Oyebode, B. Graham-Kalio and R. Orji, Heart Health: a persuasive mobile app for mitigating the risk of ischemic heart disease, Persuasive Technology. Designing for Future Change: 15th International Conference on Persuasive Technology, PERSUASIVE 2020, Aalborg, Denmark, April 20-23, 2020, Proceedings 15, Springer International Publishing, 2020, pp. 126-138.

G. Paré, C. Leaver and C. Bourget, Diffusion of the digital health self-tracking movement in Canada: results of a national survey, Journal of Medical Internet Research 20(5) (2018), e177.

T. Patel, J. Ivo, T. Pitre, S. Faisal, K. Antunes and K. Oda, An in-home medication dispensing system to support medication adherence for patients with chronic conditions in the community setting: prospective observational pilot study, JMIR Formative Research 6(5) (2022), e34906.

E. Paulino, D. Thomas, S. W. H. Lee and J. C. Cooper, Dispensing process, medication reconciliation, patient counseling, and medication adherence, Clinical Pharmacy Education, Practice and Research (2019), 109-120.

E. Pedersen, K. N. L. Truong, B. H. Garcia, K. H. Halvorsen, K. Svendsen, A. E. Eggen and M. Waaseth, Self-reported medication use among coronary heart disease patients showed high validity compared with dispensing data, Journal of Clinical Epidemiology 135 (2021), 115-124.

J. Redfern, G. Coorey, J. Mulley, A. Scaria, L. Neubeck, N. Hafiz and D. Peiris, A digital health intervention for cardiovascular disease management in primary care (CONNECT) randomized controlled trial, NPJ Digital Medicine 3(1) (2020), 117.

B. Riegel, V. V. Dickson and E. Vellone, The situation-specific theory of heart failure self-care: an update on the problem, person, and environmental factors influencing heart failure self-care, The Journal of Cardiovascular Nursing 37(6) (2022), 515.

P. A. Ruijten, The similarity-attraction paradigm in persuasive technology: effects of system and user personality on evaluations and persuasiveness of an interactive system, Behaviour and Information Technology 40(8) (2021), 734-746.

A. Schoenthaler, M. Leon, M. Butler, K. Steinhaeuser and W. Wardzinski, Development and evaluation of a tailored mobile health intervention to improve medication adherence in black patients with uncontrolled hypertension and type 2 diabetes: pilot randomized feasibility trial, JMIR mHealth and uHealth 8(9) (2020), e17135.

M. Schulz, N. Griese-Mammen, S. D. Anker, F. Koehler, P. Ihle, C. Ruckes and R. Wachter, Pharmacy-based interdisciplinary intervention for patients with chronic heart failure: results of the PHARM-CHF randomized controlled trial, European Journal of Heart Failure 21(8) (2019), 1012-1021.

E. Seid, E. Engidawork, M. Alebachew, D. Mekonnen and A. B. Berha, Evaluation of drug therapy problems, medication adherence and treatment satisfaction among heart failure patients on follow-up at a tertiary care hospital in Ethiopia, PloS One 15(8) (2020), e0237781.

B. Shahim, C. J. Kapelios, G. Savarese and L. H. Lund, Global public health burden of heart failure: an updated review, Cardiac Failure Review 9 (2023).

V. Silavanich, S. Nathisuwan, A. Phrommintikul and U. Permsuwan, Relationship of medication adherence and quality of life among heart failure patients, Heart and Lung 48(2) (2019), 105-110.

S. T. Simon, V. Kini, A. E. Levy and P. M. Ho, Medication adherence in cardiovascular medicine, BMJ 374 (2021).

J. Sloots, M. Bakker, J. van der Palen, M. Eijsvogel, P. van der Valk, G. Linssen and A. Lenferink, Adherence to an eHealth self-management intervention for patients with both COPD and heart failure: results of a pilot study, International Journal of Chronic Obstructive Pulmonary Disease (2021), 2089-2103.

J. J. Su and D. S. F. Yu, Effects of a nurse-led eHealth cardiac rehabilitation programme on health outcomes of patients with coronary heart disease: A randomized controlled trial, International Journal of Nursing Studies 122 (2021), 104040.

D. Tomasoni, M. Adamo, C. M. Lombardi and M. Metra, Highlights in heart failure, ESC Heart Failure 6(6) (2019), 1105-1127.

L. Whitehead and P. Seaton, The effectiveness of self-management mobile phone and tablet apps in long-term condition management: a systematic review, Journal of Medical Internet Research 18(5) (2016), e97.

J. E. Winland-Brown and J. Valiante, Effectiveness of different medication management approaches on elders’ medication adherence, Outcomes Management for Nursing Practice 4(4) (2000), 172-176.

C. Yang, D. T. F. Lee and S. Y. Chair, Validation and adaption of an information-motivation-behavioral skills model of medication adherence in older patients with multimorbidity, Patient Education and Counseling 113 (2023), 107756.

E. Zárate-Bravo, J. P. García-Vázquez, E. Torres-Cervantes, G. Ponce, Á. G. Andrade, M. Valenzuela-Beltrán and M. D. Rodríguez, Supporting the medication adherence of older Mexican adults through external cues provided with ambient displays: feasibility randomized controlled trial, JMIR mHealth and uHealth 8(3) (2020), e14680.

Published

2024-07-11

Issue

Section

Articles

How to Cite

ENHANCING MEDICATION ADHERENCE IN HEART FAILURE PATIENTS: AN EMPIRICAL STUDY OF PERSUASIVE TECHNOLOGY STRATEGIES. (2024). JP Journal of Biostatistics, 24(2), 371-397. https://doi.org/10.17654/0973514324021

Similar Articles

1-10 of 11

You may also start an advanced similarity search for this article.